Fungicidal activity of truncated analogues of dihydrosphingosine
نویسندگان
چکیده
منابع مشابه
Fungicidal activity of truncated analogues of dihydrosphingosine.
The minimal fungicidal concentration (MFC) of dihydrosphingosine (DHS), phytosphingosine (PHS), and five short-chain DHS derivatives was determined for Candida albicans and Candida glabrata. In this respect, a C15- and a C17-homologue of DHS showed a 2- to 10-fold decreased MFC as compared to native DHS (i.e. C18-DHS). DHS derivatives that were active, that is, comprising 12, 15, 17, or 18 carb...
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ژورنال
عنوان ژورنال: Bioorganic & Medicinal Chemistry Letters
سال: 2008
ISSN: 0960-894X
DOI: 10.1016/j.bmcl.2008.05.067